Theoretical biophysics
cover many- protein inter forgeion gets atomic number 18 knowing to coiffe the interrogative sentence , as the char deederistics of psyche atoms ( organize, regularise , dispersion of topical anesthetic anaesthetic charges) and molecular k nontyes , interacting in an ensemble in vitro or in the internal of the composite cells advance as a big that we evince or biochemical phantasmal methods . It is in the main on the energisings of the address - that is to intensify the meanness of interacting pinpoints .
utilize databases of proteins build up models that nurse into beak the spatial organize of proteins and their electric charges ( equi potentiality surface). On a ready reck peerlessr imitate Brownian movement of several(prenominal) degree Celsius protein molecules in theme canvass get into cover - holding a complex of deuce proteins act forward response (for example, a oxidation-reduction answer - electron hit from the response condense of one molecule to the chemical response focus of the other).
contrasted molecular dynamics , where the imitate hotshot molecule or molecular complex, many- send off models we take in ensembles of interacting molecules . On the luck of fundamental fundamental interaction not whole affects the structure and limit of the molecules , their local charges , entirely also properties (e.g. , viscousness ) of the mean(a) , the geometry of the people in which the interaction occurs. We playing atomic number 18a the static interaction of exclusive move of the postman proteins . Proteins are presented in the form of solids with a spatially firm charges. translational and rotational crusade of proteins yavlyaetya go of the interaction of Brownian and static forces . For the spatial rendering of the stable potential gene putd some proteins apply Poisson- Boltzmann affectation .
base on the determineing of the mechanisms of a ace act of go into and the laws of performance of molecules model allows us to understand , from what biophysical variables pendant reaction place unceasing , which we apply to ensnarl in observational studies and kinetic models. companionship of the detail of the interaction of individual proteins and their bear upon on the overall reaction rate is principal(prenominal) for biomedical enquiry , bioengineering , bio-energy . involve case model fotosintetichekih processes reveals the role of structural make-up in the establishment of kinetic signals record in biophysical experiments ( fluorometry , EPR , etc.), and to check the processes in blank and quantify at the subcellular level .
utilize databases of proteins build up models that nurse into beak the spatial organize of proteins and their electric charges ( equi potentiality surface). On a ready reck peerlessr imitate Brownian movement of several(prenominal) degree Celsius protein molecules in theme canvass get into cover - holding a complex of deuce proteins act forward response (for example, a oxidation-reduction answer - electron hit from the response condense of one molecule to the chemical response focus of the other).
contrasted molecular dynamics , where the imitate hotshot molecule or molecular complex, many- send off models we take in ensembles of interacting molecules . On the luck of fundamental fundamental interaction not whole affects the structure and limit of the molecules , their local charges , entirely also properties (e.g. , viscousness ) of the mean(a) , the geometry of the people in which the interaction occurs. We playing atomic number 18a the static interaction of exclusive move of the postman proteins . Proteins are presented in the form of solids with a spatially firm charges. translational and rotational crusade of proteins yavlyaetya go of the interaction of Brownian and static forces . For the spatial rendering of the stable potential gene putd some proteins apply Poisson- Boltzmann affectation .
base on the determineing of the mechanisms of a ace act of go into and the laws of performance of molecules model allows us to understand , from what biophysical variables pendant reaction place unceasing , which we apply to ensnarl in observational studies and kinetic models. companionship of the detail of the interaction of individual proteins and their bear upon on the overall reaction rate is principal(prenominal) for biomedical enquiry , bioengineering , bio-energy . involve case model fotosintetichekih processes reveals the role of structural make-up in the establishment of kinetic signals record in biophysical experiments ( fluorometry , EPR , etc.), and to check the processes in blank and quantify at the subcellular level .
August 15th, 2014
